No clue what's happening!!

Hi i dont have any knowledge about ur problem , still i just came here to say... calm down, relax... stress will make the situation worse... bouncing this thread so that some one can help....

 

Hey OP ,

please be calm and pray to god. Recently my bhabhi conceived after 10 year of marriage Naturally. She had visited to all big hospitals, 7 years of treatment and 3 failed IVFs. My brother had lost all faith and even cut off from all relatives. But now we got good news...we all are praying for her healthy child.

 

I think you need to ask dr on the quality of the egg prior to transfer, was it kept our to see if it multiply. If yes then the next thing will be ur uterus condition, food taken, ur sugar level, any blood cloth seen during ultrasound/ scanning.

 

Hello Brinda,
Sorry to hear about your spotting. I heard spotting is common is early pregnancy so don't lose hope yet.
Was your DH DNA fragmentation too high ? If everything is fine from ur side like egg quality ,uterine quality and karyotypes then early miscarriage may b due to very high Dna fragmentation. This can b treated by antioxidants like high vit c , e and l-carnitine.
sometimes even simple clotting issues can lead to it.

I hope your spotting is just early pregnancy spotting and hope the little embryo sticks and grows well. If things don't turn as expected sit with doctor and discuss about his Dna fragmentation issues and rule out clotting, infection and elevated Nk cells issues. Also IVF is a number game and sometimes doctors can't determine the cause of its failure.

 

Sorry I missed reading ur Dh's SA normal since two yrs. Have you both done your karyotype ? It's to rule of chromosomal problems just in case. Like I said in my earlier post rule out the probabilities of clotting issue, hidden infection and immune issues. If everything is normal then u can try Pgs on embryos just to make sure they are euploid.

 

Brinda,

karyotype problems occur very rare. Even if there is any problem Pgs testing can b done and chromosomal normal embryos will b transferred. It's normally done when sperm count is very low or very poor egg quality or repeated early miscarriage or chemical. Your doctor will recommend if she/he thinks you need one.
Nk testing is rarely done in clinics in chennai but some clinics do intralipds as a treatment. You need to check with ur dr/clinic for more info. I think doctor mainly concentrate on clotting issues and thyroid and anti thyroid antibodies and lining issues first. Regarding testing for infection I remember reading post in this forum and other forum abt ladies going to this test but I don't have more info abt it. Sorry.
since yours is unexplained plz have a healthy life style and normal bmi and keep trying naturally too.

 

Can you do PGS screening of your embryos? Often not all embryos created by IVF will be chromosomally normal, even though they look great under the microscope. Once you are certain that you are transferring normal embryos then it may be time to look into other factors like immune issues or uterine structure.
However it can often take several tries for IVF to succeed. It is better to be proactive and ask your doctor about what to do next.
Is your TSH level being monitored? Insist that it be around 1.0 if its not already. My clinic will not start IVF if the level is over 2.5, but they recommend keeping it around 1.0 while TTC.